Today i'll present a brief description about an entity called ' drug-induced-lupus '.
Certain drugs,most notorious of them being anti-arrythmic drugs like procainamide,propafenone,disopyramide,antihypertensives like hydralazine etc.
This condition usually presents with fever,lethargy,arthralgia[joint pain],arthritis,myositis etc.Drug-induced lupus is usually positive for ANA and negative for anti-dsDNA.ANA becomes positive even before the symptoms appear.[for information on ANA and anti-dsDNA,please refer to my previous post]
Other drugs causing drug-induced lupus are are...
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antibiotics like minocycline,isoniazid; diuretics like hydrochlorothiazide,anti-thyroid drugs like propylthiouracil,statins like simvastatin,lovastatin;interferons and tumor necrosis factor[TNF] and many others.
One special feature os drug induved lupus is, it is positive for anti-histone antibodies.
For any more information on this, please consult your doctor or you may post in the comment section.
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2 comments:
This is very interesting. Drugs cause so many problems, probably more than we'll ever find out. I have a new blog, undergroundhealthsecrets.info, please check it out, entrecard won't let me list it so I'm not too sure how to promote it. Any how I'll do some research and write a post on this subject. Just found out that a friend has neuropathy and she's had tons of tests to figure out why, last night I discovered that statin drugs can cause it, guess what? She takes statins...nobody told her! Paid for plenty of testing though!
Thank you for such an important and informative post. Yikes...so many women get Lupus once they begin to enter Menopause or have a very traumatic illness of other sorts. This is the first I heard of it being drug induced. That is very scary and an awareness should be made loud and clear.
Thank your so much for your efforts in putting this information out there!
Have a very nice day....
DorothyL
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