MUSCULOSKELETAL CHANGES IN LUPUS

The most important musculoskeletal changes in SLE are

1.intermittent polyarthritis[periodic attacks of arthritis involving multiple joints specially the joints of hands,wrists etc.
Usually joint erosion does not occur.

2.myalgia[muscle pain]

3.Myositis[inflammation of the muscle]

4.Occasionally pain involving a single joint like hip,knee or shoulder may occur.If this occurs in any individual suffering from SLE,he or she should immediately refer to her consulting physician as this may suggest ischaemic necrosis of the involved joint,which is more common in SLE.And may also be a side effect of the drugs used in SLE like glucocorticoids,antimalarials etc.

If any of my friends,need further information on this topic please discuss with your doctor.For any question on this topic, feel free to post in the comment section.


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SKIN CHANGES IN SYSTEMIC LUPUS ERYTHEMATOSUS

The most common skin lesion in SLE is an erythematous [reddish], slightly raised rash occuring over the face,ear,chin ,neck,upper back etc.This rash occurs most commonly in the region of the cheek and the nose [the so called ‘butterfly rash].The exacerbation of these lesions are often associated with systemic flare of SLE.

There is another entity called the subacute cutaneous lupus erythematosus [SCLE].In SCLE highly photosensitive, psoriasis like lesions with circular red margins tend to occur.

Other skin lesions that are seen in SLE are recurring urticaria,bullae[large vescicle like lesion],small ulcers within the oral cavity resembling aphthous ulcers etc.

If any of my friends,need further information on this topic please discuss with your doctor.For any question on this topic, feel free to post in the comment section.


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