Google Dec 6, 2008 | Web Health Directory

06 December, 2008

CRANBERRY:ROLE IN URINARY TRACT INFECTION

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GOOD MORNING FRIENDS.Today i thought of posting a brief review on the role of cranberry in the prevention and treatment of urinary tract infection.

Urinary tract infection is very common condition ,specially effecting females.But it also occurs in males.It is more common in women of reproductive age group,specially in sexually active women.
It is usually an easily treatable disorder,responds quickly to antibiotics.Most of the urinary tract infections are urethritis and cystitis[infection & inflammation of the urethra & urinary bladder] .Although, in some cases,pyelonephritis[infection of the kidney] may occur.

Symptoms:1.Urgent desire to to empty the bladder.[urgency]
2.increased frequency of micturition[urination]
3.pain & burning sensation during urination[dysuria]
4.if the kidney,gets involved, there may be abdominal pain,flank pain,nausea,fever,chills.

MOST COMMON BACTERIA CAUSING URINARY TRACT INFECTION IS E.coli.However there are many others[i'll try to explain, in my later posts]

ROLE OF CRANBERRY:[Vaccinium macrocarpon] has been on the scene for ages.It was also used by the native americans,for prevention and treatment of urinary tract infection.Several theories have been given to explain it's mode of action.It is believed that cranberry juice produces hippuric acid, that acidifies the urine,thereby preventing urinary tract infection.
Recent view is that,cranberry prevents specifically the attachment or adherence of E.coli to the lining epithelium of the urinary tract by inhibiting the haemagglutinition of E. coli by expression of P adhesin.[this is a molecule produced by E.coli which helps in attachment]

Although CRANBERRY has been used for many years for the treatment of urinary tract infection, but evidence is lacking [in the form of studies & trials] , to substantially prove it's role in the treatment of urinary tract infection.
But several studies have established it's role in prevention of urinary tract infection.A substantial portion of women,who have suffered from an attack of UTI,have recurrences.These individuals may benefit the most from cranberry juice.Cranberry is also available in the form in the form of capsules.

SAFETY:It is usually well-tolerated.It is usually safe.But it may have a tendency to increase the urinary oxalate level.Thus, it should be cautiously used, in individuals with history of oxalate stones.

OTHER ROLES:cranberry may also have some protective role in dental plaques.It may also have some role against fungus[dermatophytes].But these actions have not been substantially proved yet.

For further information you may discuss this issue with your doctor or visit the CNN HEALTH SITE
here OR NCBI SITEhere
IN MY OPINION,ALTHOUGH,IT'S A HERBAL MEDICINE DON'T TAKE THIS,WITHOUT PRIOR DISCUSSION WITH YOUR DOCTOR.
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