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Insulin resistance syndrome or syndrome X is a condition seen in individuals with type 2 diabetes mellitus.It is characterized by hyperglycemia[that is the blood glucose level is raised].hyperinsulinemia[the blood insulin level is also raised],dyslipidemia[abnormality in lipid profile]] and hypertension.This condition takes place due to a defect in the genes that leads to insulin resistance.Syndrome X is exaggerated by obesity and this syndrome may predispose to atherosclerosis,coronary artery disease,cerebral infarction etc
Insulin resistance means....
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that insulin,the hormone that reduces the blood glucose can not act on the target organs,thereby leading to increased blood glucose level.The increase in blood glucose level further increases the secretion of insulin as a compensatory mechanism[which fails to decrease the glucose level due to insulin resistance].Excess insulin may trigger dyslipidemia by elevating the blood triglyceride level.Hyperinsulinemia also causes sodium retention in the kidney,thus elevating blood pressure.
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