HAEMATOLOGICAL CHANGES IN LUPUS

Today,I'll discuss about the blood or hematological changes in LUPUS[Systemic lupus erythematosus].The usual change that is observed is anemia[deficiency of the red blood cells or RBCs and/or hemoglobin which is a pigment present within the RBCs which plays a role in the oxygen transport].The anaemia observed in SLE is usually normochromic,normocytic[this means the size and color of the RBCs remain unaltered].

The white blood cell[leucocytes or WBCs] count is often decreased[leucopenia],but usually the lymphocyte[a type of white blood cell] count is decreased,the granulocyte count usually remains unaltered.This usually does not increase the chance of infection.

Thrombocytopenia or reduction of platlet count may be seen.
In some individuals suffering from SLE hemolysis or destruction of the red blood cells may occur.

For any more information on this, please consult your doctor or you may post in the comment section.

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CARDIOVASCULAR CHANGES IN PREGNANCY

Good morning friends,starting from this post onwards i will try to explain some changes the human body undergoes during pregnancy.Today I'll make an attempt to explain the cardiovascular changes in pregnancy[heart & the circulatory system]

Pregnancy is a hyperdynamic state of circulation.
1.Blood volume increases by almost 40-50%.[peaks in 28-32 weeks of gestation]
2.Plasma volume increases to the tune of 40%.
3.Anemia[due to discrepapancy of the rise of blood volume & plasma volume and also due to iron deficiency]
4.Decreased oxygen carrying capacity of blood.[this is compensated by several mechanisms like increase in cardiac output,decreasing blood viscosity,vessel dilatation etc]
5.Due to the effect of estrogen & progesterone[these hormones rise during pregnancy] dilates the blood vessels so there is a fall in the resistance offered by the blood vessels[systemic vascular resistance & pulmonary vascular resistance]
6.Increase in cardiac output[peaks during 22-28 weeks of gestation].
7.Increase in stroke volume[the blood pumped by the heart with each heart beat].
8.Red blood cell volume also increases to the tune of 20%.
9.heart beat increases during pregnancy by 12-16beats/minute[this may give rise to palpitation i.e becoming conscious about your heart beat]
10.Alteration of blood pressure:Systolic blood pressure and diastolic blood pressure,both fall to a minor extent,but the changes are more marked in diastolic blood pressure.
11.Pedal edema[swelling around the ankles,which pits on application of pressure].
12.Some ECG changes.[ST-T changes]
13.some findings are also observed on auscultation of the heart[examination of the chest with a stethoscope] like murmurs,increased splitting of heart sounds,S3 gallop etc.
14.Decrease in blood viscosity.
15.Shift of the oxygen hemoglobin dissociation curve to the right.

PLEASE DISCUSS THIS ISSUES WITH YOUR DOCTOR OR FOR FURTHER INFORMATION ON THIS YOU MAY Visit here

Yes,i know i could not explain a few terms in a more simple way ,because i thought they will be a bit out of the extent of this post,but still if you find this post informative,please subscribe.
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