TYPE 2 ENDOMETRIAL CANCER

Type 2 endometrial cancers which consists of three types: uterine papillary serous carcinoma,mucinous carcinoma,anaplastic carcinoma is much rarer than the much more commoner type 1 ,sub-group of endometrial cancer that comprises of endometrioid carcinoma,mucinous carcinoma etc.

Endometrioid cancer[type 1] is the most common type of endometrial cancer .The risk factors of endometrial cancer are factors that increases the body’s exposure to estrogen like estrogen replacement therapy, diabetes,hypertension,hyperlipidemia etc.It occurs in the background of endometrial hyperplasia.

Type 2 endometrial cancers, the most common of which is uterine papillary serous carcinoma, does not depend on body’s exposure to estrogen but actually develops in a background of atrophic endometrium .This type of endometrial cancer actually develops in older age than the commoner endometrioid endometrial cancer and carries a much poorer prognosis than endometrioid cancer.The pre-cancerous lesion is thought to be endometrial intra-epithelial carcinoma [EIC].

For further information please discuss this issue with your doctor.For any more querries on this. please feel free to ask , in the comments section.
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UNDULANT FEVER:BRUCELLOSIS

Good evening friends,today I'll post a brief review of BRUCELLOSIS or UNDULANT FEVER or MALTA FEVER.

Brucellosis is a zoonosis, that primarily effects animals like goats,cows,pigs etc.Brucellosis is caused by a bacteria called Brucella, a gram negative coccobacilli.

Human beings are primarily effected by direct contact with infected animals flesh or other body parts like placenta or ingestion of food contaminated with infected products.

Individuals who are most likely to become infected are individuals working in meat packing industry[abattoir worker], a veterinarian,a farmer or traveler consuming dairy products etc.

SYMPTOMS:Individuals with brucellosis usually present with fever,chills,weakness,sweats,backache,headache etc.
The individuals experience a fever which peaks in the evening and gradually subsides by morning, thus called undulant fever.

DIAGNOSIS: Is made by blood culture or culture from bone marrow,liver etc.

TREATMENT:1. Doxycycline
2.doxycycline & rifampicin
3.Doxycycline & streptomycin
4.child- trimethoprim-sulphmethoxazole & aminoglycosides.

INDIVIDUALS WHO BELIEVE TO BE AT RISK ,PLEASE DISCUSS THESE ISSUES WITH YOUR DOCTOR.FOR MORE INFORMATION THEY MAY VISIT THE WIKIPEDIA SITEhere

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