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21 June, 2009

GRAFT VERSUS LEUKEMIA EFFECT

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Electron microscopic image of a single human l...Image via Wikipedia

Acute graft versus host disease is a condition in which the graft versus host reaction occurs in the first 3 months of the transplant procedure.Usually it appears in the first 2-4 weeks following transplant.Acute graft versus host disease is characterized by erythematous[reddish] maculopapular skin lesions,anorexia,diarrhea and dysfunctions of the liver with rise in serum bilirubin,SGOT,SGPT.Acute graft versus host disease has been into four stages and four grades.


Acute graft versus host disease is mediated by the T lymphocytes[a variety of blood cell] present in the donor marrow.If the recipient that is an individual who receives the transplant, is transfused with bone marrow depleted of donor T cells,then the chances of Acute graft versus host disease is virtually eliminated.But by this process,the chances of failure of engraftment[graft failure] increases and recurrence of disease in leukemic patients increases.This is called graft versus leukemia effect.

For more information on this,please discuss with your doctor and visit other reliable internet sources, or may post any question in the comment section.



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18 June, 2009

obesity

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The actual definition of obesity is a state of excess deposition of adipose[fatty] tissue mass within our body.The most widely used measure to estimate obesity is the body mass index[BMI].

BODY MASS INDEX is defined as the ratio of the weight in Kgs[kilograms] divided by the square of the height in metres[m x m]

UNDERWEIGHT : BMI less than 19.8

NORMAL WEIGHT: BMI between 19.8 to 26

OVERWEIGHT: BMI between 26 to 29

OBESE: BMI above 29

MORBIDLY OBESE: BMI exceeds 35

Obesity has been linked with many of the lifestyle diseases like diabetes,hypertension,Hypercholesterolemia[high cholesterol],heart diseases.
Few very easy steps like controlled diet,exercise can easily control this surge of obesity.

By controlled diet,i mean there should be a proper balance of nutrients,vitamins,minerals,carbohydrates and proteins.Junk foods should be limited to a minimum.

The amount of extra calories that an individual consumes through his/her diet should be burnt out by means of exercise.Exercise should be a part of our daily routine.Half an hour of walking,sprinting,swimming every day depending upon an individual's physical requirement and capacity,is a very good exercise.

But in this fast paced world we usually do not get that time.Indoor exercises like walking on a treadmill,Agile DMT Elliptical,cycling on exercise-bikes is a effective alternative.Another benefit of these fitness equipments are that they are provided with BMI calculator,heart rate control,adjustable chest straps for user convenience.Other accessories like Multi Color LCD Display,Built in Adjustable Fan,iPod Docking Station with Speakers have also beed provided.

Overall proper dieting and exercise are the two most important measures to control obesity.




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